2015 Gastroenterology: Sox9 & rISCs
2015 FASEB J: IGF1 Activation of ISCs
2015 Nature CB: Stem Cell Niche
2014 Dev Cell: Mesenchymal Stem Cell
2014 AJP-GI: ISC Hierarcy Review
2014 Endocrinology: Obesity ISCs
2014 J Biol Eng: 3D Colon Culture
2014 Lab on Chip: Ex vivo Colon
2013 Lab on Chip: Crypt Culture
2013 AJP-GI: Multi-Center FACS
2013 PLoS One: Porcine ISC Culture
2013 Gastroenterology: ISC Culture
2013 Stem Cells: Human ISC Iso/Cult
2013 Nature: YAP
2012 PLoS One: Fibrosis
2012 Methods Mol Biol: ISC Culture
2012 AJP-GI: ISC Nomenclature
2012 AJP-GI: ISC Irradiation
2012 AJP-GI: POLG2257A mutant ISC
2012 Development: Notch ISCs
2011 AJP-GI: Sox9 Colon/Colonoids
2011 AJP-GI: Sox Review
2011 AJP-GI: CD24 ISC Marker
2010 PLoS One: Inflammation
2010 AJP-GI: CD24 ISC Enteroids
2010 AJP-GI: Sox9 ISC Marker
2008 Endocrinology: IGF Colon Tumor

Abstract
The dermal papilla (DP) provide instructive signals required to activate epithelial progenitors and initiate hair follicle regeneration. DP cell numbers fluctuate over the hair cycle, and hair loss is associated with gradual depletion/atrophy of DP cells. How DP cell numbers are maintained in healthy follicles remains unclear. We performed in vivo fate mapping of adult hair follicle dermal sheath (DS) cells to determine their lineage relationship with DP and found that a subset of DS cells are retained following each hair cycle, exhibit self-renewal, and repopulate the DS and the DP with new cells. Ablating these hair follicle dermal stem cells and their progeny retarded hair regrowth and altered hair type specification, suggesting that they function to modulate normal DP function. This work identifies a bipotent stem cell within the adult hair follicle mesenchyme and has important implications toward restoration of hair growth after injury, disease, and aging.
Rahmani w, Abbasi S, Hagner A, Raharjo E, Kumar R, Hotta A, Magness S, Metzger D, Biernaskie J.
Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type
Developmental Cell, 2014 Nov 26. pii: S1534-5807(14)00688-1